Polynt Group produces a great variety of anhydrides, but the most important ones are: Phthalic Anhydrides, Maleic Anhydride, Trimellitic Anhydride Environmental: Maleic anhydride's fate in soil is unknown. Maleic anhydride undergoes a potentially explosive exothermic Diels-Alder reaction with 1-methylsilacyclopenta-2,4-diene at 150C [Barton, T. J., J. Organomet. exposure may cause allergic respiratory reaction (asthma). Colorless needles, white lumps, or pellets with an irritating, choking odor. Chemical name :maleic anhydride Substance/mixture : Occupational exposure limits, if available, are listed in Section 8. Chemical safety data sheet sd-88: properties and essential information for safe handling and use of maleic anhydride. MALEIC ACID page 2 of 6 This Fact Sheet is a summary source of information of all ... (as Maleic Anhydride) exists, use a MSHA/NIOSH approved self-contained breathing apparatus with a full facepiece operated in a … Causes redness and pain. Combustible Solid, but may be difficult to ignite. A combination of these processes should be important. FIRST AID MEASURES General advice Consult a physician. 108 -31 -6 203 -571 -6 607 -096 -00 -9 - 4. : 108-31-6 Molecular Weight: 98.06 Chemical Formula: C4H2O3 Company: ADDTEK CHEMICAL SHANGHAI CO LTD TEL: +86 21 63352916 FAX: +86 21 51010033EXT8839 : 108-31-6 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. Memorandum. Click here for information on selection of N, R, or P filters.Any appropriate escape-type, self-contained breathing apparatus, Important additional information about respirator selection, cis-Butenedioic anhydride, 2,5-Furanedione, Maleic acid anhydride, Toxilic anhydride. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Potential Health Effects MATERIAL SAFETY DATA SHEET MALEIC ANHYDRIDE 1. Product name : Maleic Anhydride CAS-No. irritation with nausea, vomiting, and diarrhea. May cause asthmatic attacks due to allergic sensitization of the skin. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Exposure to maleic anhydride may occur from accidental releases to the environment or in workplaces where it is produced or used. Maleic anhydride has several uses, almost all of them related to the synthesis of other chemicals as fumaric and tartaric acids, certain agricultural chemicals (i.e., maleic hydrazide, malathion), lubricants, surface active agents, resins in different products, dye intermediates, pharmaceuticals, and more. Maleic anhydride CAS -No. Anhydrides. : 607-096-00-9 CAS-No. Reproductive Toxicity: No data available Reproductive toxicity - Rat - Oral ... Maleic anhydride is transported also as hot liquid (70°C); contact of the skin should be avoided. The anhydride of maleic acid has five atoms in its cyclic molecule, the unsaturated bond undergoes free radical polymerization in the presence of an initiator. NCI [1974]. Maleic acid 110-16-7 >95 4. A poison by intravenous route. May cause skin sensitization, an allergic Maleic anhydride in daily doses of 20, 40,100, 250 or 600 mg/kg body weight, fed for 90 days to groups of 15 rats of each sex, caused macroscopic changes in the kidneys: enlargement and pale yellow discoloration. Wash out mouth with water. Evaporate the chloroform in a hood. Target Organs: Lungs, respiratory system, eyes, double vision, and "halo" vision. Product name : Maleic anhydride Product Number : 63200 Brand : Sigma-Aldrich Index-No. none Water, Foam, Alcohol resistant foam, ABC-powder Water jet Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO2) In … Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Immediate medical attention is required. If not breathing, give artificial respiration. SAFETY DATA SHEET (in accordance with Regulation (EU) 2015/830) 108120-Maleic anhydride Version: 3 Revision date: 19/04/2016 Page 2 of 9 Print date: 19/04/2016 -Continued on next page.- P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Product Safety Assessment: Maleic Anhydride Last Revised: August 2015 Page 2 of 3 Potential Human Health Effects Occupational Exposure Potential for occupational exposure to Maleic Anhydride exists during manufacture, at transloading, storage and staging areas, and during mixing and sampling operations in the manufacture of other products. Chronic: Up to 10 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode£(APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece, Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus, Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. "Maleic Anhydride, Maleic Acid, and Fumaric Acid." [Note: Reacts slowly with water (hydrolyzes) to form maleic acid. When heated to decomposition it emits acrid smoke and irritating vapors. Corrosive. Pesticide properties for Maleic hydrazide, including approvals, environmental fate, eco-toxicity and human health issues Symptoms and effects are not known to date. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Hazard classification & labelling Hazard classification and labelling. May cause conjunctivitis. Interagency Collaborative Group on Environmental Carcinogens. Rinse mouth with water (only if the person is conscious). MCA [1974]. You will be subject to the destination website's privacy policy when you follow the link. Recrystallize the maleic anhydride from toluene. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Eye: Inhalation: National Cancer Institute, June 17, 1974. Prolonged or repeated skin contact may cause dermatitis. reaction, which becomes evident upon re-exposure to this material. Wear safety goggles or eye protection in combination with breathing protection if powder. Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-9974 Causes redness and Danger! Safety Statements :26-36/37/39 Harmful if swallowed. Causes skin burns. If inhaled If breathed in, move person into fresh air. burns. Appearance: white lumps. Move out of dangerous area. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Maleic anhydride TWA: 0.01 mg/m 3(Vacated) TWA: 0.25 ppm (Vacated) TWA: 1 mg/m3 TWA: 0.25 ppm TWA: 1 mg/m3 IDLH: 10 mg/m TWA: 0.25 ppm TWA: 1 mg/m3 TWA: 0.01 ppm Legend ACGIH - American Conference of Governmental Industrial Hygienists OSHA - Occupational Safety and … Substance Any concentration shown as a range is to protect confidentiality or is due to batch variation. Show this safety data sheet to the doctor in attendance. Moisture sensitive. May cause blistering of the skin. Strong oxidizers, water, alkalis, metals, caustics & amines above 150°F The odour warning when the exposure limit value is exceeded is insufficient. cis-Butenedioic anhydride, 2,5-Furanedione, Maleic acid anhydride, Toxilic anhydride Colorless needles, white lumps, or pellets with an irritating, choking odor. +86-532-8027466 SECTION 1: PRODUCT AND COMPANY IDENTIFICATION ... Acrylic acid maleic anhydride copolymer, aka: 2-propenoic acid, polymer with 2,5, furandion e (cis-butenedioic anhydride) 52255-49-9 : ... Acrylic Acid Maleic … (5,8) The vapor pressure for maleic anhydride is 0.1 to 0.2 mm Hg at 25 °C. Maleic anhydride, polymers Safety Profile. First Aid Measures Description of Firstaid Measures General Advice: Consult a physician. Causes severe eye and skin irritation with possible Inhalation of high concentrations may cause pulmonary edema. 5. Causes respiratory Maleic anhydride released into water will hydrolyze rapidly (half-life 0.37 min) to maleic acid. ], inhalation, ingestion, skin and/or eye contact, irritation nose, upper respiratory system; conjunctivitis; photophobia (abnormal visual intolerance to light), double vision; bronchial asthma; dermatitis, Centers for Disease Control and Prevention. : 108-31-6 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Manufacture of substances 1.3 Details of the supplier of the safety data sheet Causes chemical burns to the respiratory tract. P342+P311 If experiencing respiratory symptoms: Call a POISON CENTER/doctor. Safety Data Sheet (Maleic Anhydride) DATE PREPARED: 9/3/2015 Page 7 of 9 OSHA: No component of this product, present at levels greater than or equal to 0.1%, is identified as a carcinogen or potential carcinogen by OSHA. Maleic anhydride is a colorless to white solid that forms orthorhombic crystals and decomposes in water. Index -No. Stir the mixture for 10 min. (2) Conversion Factors: Maleic Anhydride 95 - 100% 108-31-6 Get medical attention immediately. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in … EC -No. Exposure to high fume concentrations cause photophobia, (2) Maleic anhydride has an acrid odor, with an odor threshold of 0.32 parts per million (ppm). pain. Product identifier Identification number Name of the substance Maleic anhydride 607-096-00-9 (Index number) Registration number 01-2119472428-31 Synonyms MAN Issue date 07-March-2019 Version number 01 Revision date-Supersedes date-1.2. Ingestion: Safety Data Sheet 24 hour Emergency Response No. OSHA Vacated PELs: Acetic anhydride: No OSHA Vacated PELs are listed for this chemical. Immediate medical attention is required. SAFETY DATA SHEET SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Common Name Maleic Anhydride Synonym(s) 2,5Furandione Formula C 4 H 2 O 3 CAS Number 108316 COMPONENT CAS NUMBER CONCENTRATION Maleic Anhydride 108316 ≤ Section 4. Environmental: Maleic anhydride's fate in soil is unknown. Acute (short-term) inhalation exposure of humans to maleic anhydride has been observed to cause irritation of the respiratory tract and eye irritation. The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. Remove victim to fresh Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Risk Statements: 36/37/38 R36/37/38:Irritating to eyes, respiratory system and skin. Chem., 1979, 179, C19], and is considered an excellent dieneophile for Diels-Alder reactions [Felthouse, Timothy R. et al. May cause allergic skin and respiratory reaction. Maleic anhydride is used in the formulation of resins. Maleic Anhydride Flinn Scientific, Inc. P.O. Causes gastrointestinal tract burns. 6. Repeated May cause digestive tract Dissolve the residue in a minimal amount of chloroform. Consult a physician. Causes eye burns. Washington, DC: Manufacturing Chemists Association, p. 1-13. respiratory tract. safety hazards of Maleic Acid to potentially exposed workers. CDC twenty four seven. System RfD (mg/kg-day) Basis PoD Composite UF Confidence; Urinary: 1 x 10 -1: Renal lesions: NOAEL : 1.0 x 10 1 mg/kg-day Do NOT induce vomiting. Skin: Add 0.98 g (0.01 mole) of maleic anhydride to a solution of 1.67 g (0.01 mole) of veratrylamine in 10 mL of chloroform. Product Identification Synonyms: cis-Butenedioic anhydride; 2,5-furandione; toxilic anhydride CAS No. Histological examination revealed nephrosis which increased in severity with the dose above 100 mg/kg. Maleic Anhydride Safety Data Sheet International Diol Company SAFETY DATA SHEET according to Regulation (EC) No. First-aid measures General Advice Show this safety data sheet to the doctor in attendance. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. tract irritation and possible burns. Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH), National Institute for Occupational Safety and Health, A – NIOSH Potential Occupational Carcinogens, E – OSHA Respirator Requirements for Selected Chemicals, G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect, Type C & CE – Definitions for Type C and Type CE Respirators, U.S. Department of Health & Human Services. 1272/2008, Regulation (EC) No.1907/2006 Maleic Anhydride, rev 2 7/2012 Page 2 Basis for Classification This substance is classified based on Directive 1272/2008/EC and its amendments (CLP Regulation,GHS) MALEIC ANHYDRIDE (108-31-6) Harmful if swallowed. Vacated PELs: Acetic anhydride: No osha Vacated PELs: Acetic anhydride No... The maleic anhydride is 0.1 to 0.2 mm Hg at 25 °C cis-Butenedioic anhydride ; 2,5-furandione ; anhydride... A minimal amount of chloroform listed for this chemical, for at least 15 minutes from toluene attest to environment. 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